Category Archives: Grants

IPAS Novel PPARγ Antagonist – the answer for more effective and safer Type II Diabetes treatment

IPAS researchers have been investigating safer drugs against type two diabetes which are effective at increasing insulin sensitivity without causing side effects. The team has successfully used a number of analytical techniques to determine how these new and improved drugs interact with their target in the body. Their work builds on from previous research undertaken by themselves and others around the globe which focusses on a critical aspect on the development of what can often be a debilitating or even life-threatening condition.

PPARγ in Complex with an Antagonist and Inverse Agonist: A Tumble and Trap Mechanism of the Activation Helix
Rebecca L. Frkic, Andrew C. Marshall, Anne-Laure Blayo, Tara L. Pukala, Theodore M. Kamenecka, Patrick R. Griffin, John B. Bruning
DOI: https://doi.org/10.1016/j.isci.2018.06.012

 

 

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IPAS laser featured in Physical Review Applied

breathIPAS research group led by Prof Andre Luiten has created a laser that can differentiate gas compounds with high accuracy and precision. This technique not only finds ground breaking applications in environmental monitoring and  industrial contamination but also paves the way for early stage medical diagnostics.

Number-Density Measurements of CO2 in Real Time with an Optical Frequency Comb for High Accuracy and Precision.
Sarah K. Scholten, Christopher Perrella, James D. Anstie, Richard T. White, Waddah Al-Ashwal, Nicolas Bourbeau Hebert, Jerome Genest, and Andre N. Luiten
Phys.Rev.Applied 9, 054043
DOI: 10.1103/PhysRevApplied.9.054043

 For full media release, please click here.

GLASS CAN BE BOTH SCIENCE AND ART featured in ATSE’s focus magazine

Congratulations Prof Heike Ebendorff-Heidepriem on being selected to be included in this month’s addition of the Australian Academy of Technological Sciences and Engineering (ATSE)’s Focus magazine.

This edition of ATSE Focus contains a selection of profiles of recipients of the first round of Global Connections Fund Priming Grants, which demonstrate the diversity of projects and partnerships being supported by the program.Heike _ glass & art

Prof Ebendorff-Heidepriem was successfully awarded a 2017 Global Connections Fund – Bridging Grant , in collaboration with international partner IRflex, with the project entitled “Extruded Hollow-Core Fibre for High-Power Mid-IR Laser”.

For the online article, please click here.

 

Prof Abell and team featured in NHMRC top 10 for 2016!

andrew_abell_team

Inhibitors of biotin protein ligase: A new class of antibiotic targeting Staphylococcus aureus”  led by Prof Andrew Abell and his team has been awarded 1 of the best 10 NHMRC research project 2016!

This project successfully engaged chemistry and biochemistry to discover a new antibacterial by inhibiting a key protein – known as biotin protein ligase (BPL)- as a potential mechanism for limiting bacterial survival.

Congratulations to Prof Andrew Abel and team!

2017 Global Connections Fund – Bridging Grant awarded!

Congratulations to Prof Heike Ebendorff-Heidepriem on being successfully awarded a 2017 Global Connections Fund – Bridging Grant  with the project entitled ” Extruded Hollow-Core Fibre for High-Power Mid-IR Laser”. The Bridging Grants are designed to support international SME-Researcher partnerships grow beyond an initial level of engagement into a strong collaboration leading to the translation of research knowledge and intellectual property into market ready products or services.

This grant will not only accelerates the development of a long term strategic collaboration between IPAS and IRflex Corporation (USA) but it also continues to reinforce the existing collaboration to develop hollow-core fibre with the unique capability to transmit extremely high-power industrial lasers.

This project will utilise IPAS’ s unique intellectual property and know-how to design and fabricate innovative dies for glass extrusion with extremely fine microstructures (~1 micron thick); along with the 3D metal printing capabilities to develop and produce titanium dies specifically designed to extrude mid-infrared glasses. The partner company, IRflex Corporation (USA), is specialized in the development and manufacture of novel mid-infrared fibres and devices, with the specialized equipment and technical resources to produce ultra high-purity mid-infrared glasses.

 

2 IPAS Teams part of the next CSIRO ON PRIME

onCongratulations to Team Mirage Photonics and Team GLAS who are going to be part of the next CSIRO ON Prime program.

Team Mirage Photonics (comprising of Ori Henderson-Sapir, Ka Wu, Annetay Henderson-Spair, Michael Muthig & Piers Lincoln). This project will offer solutions using affordable mid-infrared moderate-power lasers to detect gases and organic compounds such as greenhouse gases and petroleum based chemicals in environmental monitoring, oil and gas development, transportation and medicine.  The team hopes to identify and approach potential customers as well as progress from technology to business.

Team GLAS (comprising of Heike Ebendorff-Heidepriem, Tim Zhao, Yunle Wei, Francois Duvenage, Elodie Janvier & Karen Cunningham). This project will  develop a technique named GLAS (G:Green, L:Large-scale, A: All-in-one, S: Simple) which will endorse a range of color codes in glass via striking noble metal nano particles in a highly controllable manner instead of using toxic chemicals such as heavy metals. This program will bring academia and business/industry partners together to meet practical needs and solve real-life problems. It also helps to build up connections with partners and customers.

Congratulations to both team!

Timely Success to Build High-Performance Clocks

Screen Shot 2017-07-07 at 11.18.46 am

Dr Chris Perrella (Precision Measurement Group) was recently awarded a  Global Connections Fund Priming Grant. The purpose of the grant is to facilitate collaborations between Australian small to medium sized enterprises (SMEs) and researchers.

This Project will develop a compact high-performance optical clock for ultra-precise timing signals by bringing together Australia’s foremost precision measurement laboratory at the Institute for Photonics and Advanced Sensing (IPAS), the University of Adelaide, and links it to the world’s leading company in optical precision measurement technology, Menlo Systems GmbH.

The compact high-performance optical clock has potential applications in: communication networks; telecommunications; global positioning systems (GPS); and inertial navigation systems.

Excellence in Research Award for Dr Jiawen Li

jiawen-li Congratulations Dr Jiawen Li, who recently won a Women’s Research Excellence award.

She will be using the award to assist with travel to RMIT and Hong Kong Polytechnic University, where she hopes to build on exisiting collaborations.

ARC Future Fellowship for Dr Jonathan George

jonathan georgeCongratulations to Dr Jonathan George on receiving an Australian Research Council (ARC) Future Fellowship.

Jonathan will be using marine microorganisms to study the biosynthesis of usual antibiotic products, hopefully resulting in the creation of new antibiotics. Currently a senior lecturer in the School of Chemistry,  Jonathan will receive $820 000 for salary and research support over a four year period.

 

Project details: 

“Using natural products to inspire discoveries in synthesis and biosynthesis. This project aims to understand the organic chemistry that occurs in the biosynthesis of unusual antibiotic natural products by marine microorganisms. In an interdisciplinary approach, proposed biosynthetic intermediates will be synthesized and screened against newly isolated enzymes from the microorganisms of interest. This will allow the elucidation of biosynthetic pathways, and aid the discovery of new chemoenzymatic reactivity that may be broadly useful in organic synthesis. Non-enzymatic, predisposed organic reactions will also be uncovered during the project. The benefit of this project will be an improvement in our ability to synthesise potential antibiotics using a combined synthetic organic and chemoenzymatic approach. This could lead to useful new antibiotics in the future.”

ARC Future Fellowships are aimed at allowing outstanding mid-career researchers to stay in Australia and encourage research in areas of national priority.

A comprehensive list of other successful Future Fellowships can be found here.

Radiation Sensing and Optical Clocks Wins Support from DSTG

Dr Ruth Shaw (Institute for Minerals and Energy Resources) and Dr Chris Perrella (Precision Measurement Group) recently received funding from the Defence Science and Technology Group’s (DSTG) competitive evaluation research agreement (CERA) scheme.

Announced by the Minister for Defence Industry, the Honorable Christopher Pyne MP, CERA funding “allows us to draw on the expertise in Australian universities to initiate research into emerging technologies of interest to Defence,” Minister Pyne said.

The two successful projects from IPAS members were:

Chris Perella.Dr Chris Perrella (CI), Dr Fred Baynes, Dr Phil Light, Dr Ben Sparkes, Prof Andre Luiten & Belinda Pickett (DSTG)

High-Performance Optical Clock for Local Time References and UAV Applications

This project will develop an atomic, optical clock that will provide local timing signals used for navigation in the absence of global positioning systems (GPS) signals. The optical clock offers significant benefits over clocks currently used in GPS in terms of size, weight, power consumption, and their intrinsic performance. This kind of precision and high-stability timing signals are required for GPS and inertial navigation systems, and the optical clock will further minimise the risks of intentional jamming/spoofing or  other limitations in GPS access.

Ruth_Shaw2.jpgDr Ruth Shaw (CI), Prof Heike Ebendorff-Heidepriem, Prof Nigel Spooner, Dr Chris Kalnins, A/Prof David Ottaway and Carly Whittaker

Radiation-sensitive optical fibres for real-time distributed radiation sensing”

The project aims to characterise and use rare earth doped silica to develop sensitive fibre optic devices for the real-time monitoring of entryways associated with the transportation of radioactive material.

The media release from Christopher Pyne MP can be found here.