IPAS Best Papers for 2015

on 29 January 2016 at the IPAS New Year Event we announced winners of our “IPAS Best Papers” competition for 2015. We were inundated with entries showing the quality and impact of the research being conducted by IPAS members.

Winners for the best ECR led Paper were Abel Santos, Agnieszka Zuber and Xiaozhou (Michelle) Zhang. The best PhD Student Led Paper Awards went to Malcolm Purdey, Parul Mittal and Tess Reynolds. The Best Overall Paper Award went to Gar-Wing Truong and the Best Transdisciplinary Paper with a Strong Medical/Animal Science Element (sponsored by IVF Vet Solutions) went to Melanie McDowall.

See below for a short summary of each of these outstanding papers.

Best IPAS Paper Open Category

Gar-Wing Truong

Gar-Wing Truong

Paper Title/Authors: Accurate lineshape spectroscopy and the Boltzmann constant (G.-W. Truong, J. D. Anstie, E. F. May, T. M. Stace, A. N. Luiten)

Journal Name: Nature Communications

Summary: We developed a laser thermometer that tracks the amount of motion in cesium atoms to measure the Boltzmann constant, a fundamental quantity linking temperature to atomic motion, with world-leading precision. This work has revealed new insights into light-atom interactions and also contributes to a world-wide effort to redefine the kelvin (a unit of temperature).

 

PhD Student Led Paper Awards

Malcolm Purdey

Malcolm Purdey

Paper Title: Boronate probes for the detection of hydrogen peroxide release from human spermatozoa (Malcolm S.Purdey, Haley S.Connaughton, SaraWhiting, Erik P.Schartner, TanyaM.Monro, Jeremy G.Thompson, R. JohnAitken, Andrew D. Abell)

Journal Name: Free Radical Biology and Medicine

Summary: This work uses new fluorescent sensors to detect hydrogen peroxide in sperm. Hydrogen peroxide is an oxidant that is found in poorly motile sperm and can indicate infertility. The new sensors could distinguish poor quality sperm, and could find use detecting male infertility.

Parul Mittal

Parul Mittal

Paper Title: Proteomics of endometrial cancer diagnosis, treatment, and prognosis (Parul Mittal, Manuela Klingler-Hoffmann, Georgia Arentz, Chao Zhang, Gurjeet Kaur, Martin K. Oehler, Peter Hoffmann)

Journal Name: Proteomics- Clinical Applications

Summary: By using the state of the art technique ‘MALDI mass spectrometry imaging’ we have discriminated the regions of the healthy endometrial tissue from regions of tumors with an AUC = 0.985 [AUC expresses the discrimination power and assumes values between 0 (no discrimination) and 1 (perfect discrimination)].

Tess Reynolds

Tess Reynolds

Paper Title: Optimization of whispering gallery resonator design for biosensing applications (T. Reynolds, M. R. Henderson, A. François, N. Riesen,J.M.M. Hall, S.V. Afshar, S.J. Nicholls, T.M. Monro).

Journal Name: Optics Express

Summary: We investigated how to optimize the sensing performance of microsphere resonators using an analytical model that allows any combination of resonator diameter and refractive index to be compared. By incorporating the sensitivity and quality factor of each resonator into a new figure of merit, sensing performance can readily be optimized.

 

The Best Eearly Career Researcher Led Paper Awards

Abel Santos

Abel Santos

Paper Title: Realisation and Advanced Engineering of True Optical Rugate Filters Based on Nanoporous Anodic Alumina by Sinusoidal Pulse Anodisation (Abel Santos, Jeong Ha Yoo, Charu Vashisth Rohatgi, Tushar Kumeria, Ye Wang Dusan Losic)

Journal Name: Nanoscale

Summary: This study is the first realisation of true optical rugate filters (RFs) based on nanoporous anodic alumina (NAA). A rationally designed sinusoidal pulse anodisation was used to engineer the characteristic reflection peaks and interferometric colours of NAA-RFs with precision, which can be finely tuned across the UV-visible-NIR spectrum.

Agnieszka Zuber

Agnieszka Zuber

Paper Title: Detection of gold nanoparticles with different sizes using absorption and fluorescence based method method (Agnieszka Zuber, Malcolm Purdey, Erik Schartner, Caroline Forbes,Benjamin van der Hoek, David Giles, Andrew Abell, Tanya Monro, Heike Ebendorff-Heidepriem).

Journal Name: Sensors and Actuators B: Chemical

Summary: Growing world demand for gold necessitates developing a new, easy-to-use and fast method for detection of low concentrations of gold at the exploration drilling site. Two optical methods: absorption and fluorescence are shown to be suitable for as low detection of gold as 74ppb.

Xiaozhou (Michelle) Zhang

Xiaozhou (Michelle) Zhang

Paper Title: Photoregulation of α-Chymotrypsin Activity by Spiropyran-based Inhibitors in Solution and
Attached to an Optical Fiber (Xiaozhou Zhang, Sabrina Heng, and Andrew. D. Abell)

Journal Name: Chemistry-A European Journal

Summary: We report the development of novel photoswitchable protease inhibitors of which the activity can be switched ‘on’ and ‘off’ by light. An inhibitor of this class was attached to a microstructured  optical fibre to produce a biosensor for proteases that can be used in disease diagnosis and
treatment.

 

Best Transdisciplinary Paper with a Strong Medical/Animal Science Element (sponsored by IVF Vet Solutions)

Melanie McDowall

Melanie McDowall

Paper Title: Redox and anti-oxidant state within cattle oocytes following in vitro maturation (IVM) with bone morphogenetic protein 15 (BMP15) and follicle stimulating hormone (Melanie Sutton-McDowall, Malcolm Purdey, Hannah Brown, Andrew Abell, David Mottershead, Pablo Cetica, Gabriel Dalvit, Ewa Goldys, Robert Gilchrist, David Gardner, Jeremy Thompson)

Journal Name: Molecular Reproduction and Development

Summary: Conventional IVM is suboptimal as oocyte-derived growth factors (such as BMP15) are absent from conventional systems. While the addition of exogenous BMP15, plus hormones such as FSH, considerable improves IVM quality, the underlying metabolic profiles are unknown. BMP15 supplementation considerable improved mitochondrial activity and oxidative metabolism within the oocyte.

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Posted on February 10, 2016, in IPASnews, Paper Summaries and tagged , , , , , , , , , , , , , , , . Bookmark the permalink. Leave a comment.

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