Simultaneous observation of the metabolism of cisplatin and NAMI-A in human plasma in vitro by SEC-ICP-AES

Jason Wedding

Jason Wedding

Summary: The binding of two different anticancer drugs, NAMI A and cisplatin, to blood plasma proteins showed that both bind to the same protein yet their respective metabolism went unchanged. Single drug-based treatments are regularly hindered by the development of drug resistance by the cancer. Combination therapy, or the use of multiple drugs during treatment, but they must not interfere with each other negatively, thus therapy with these drugs warrants further trials.

Authors: Sooriyaarachchi, M, Wedding, JL, Harris, HH, Gailer, J

 JBIC Journal of Biological Inorganic Chemistry (2014)

Work done in collaboration with University of Calgary

Wedding-cisplatin

Advertisements

Posted on July 11, 2014, in IPASnews, Paper Summaries and tagged , , . Bookmark the permalink. Leave a comment.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: